It’s not a feature that can be quantified or measured. More personal.įrom the “Projects We Love” to the “Trending” page, you can browse Kickstarter every day and find something new to inspire you. Whereas Indiegogo does a good job at hosting new and fresh product ideas, Kickstarter feels more collaborative. The Kickstarter team has built a thriving community of backers and creators, big and small. It was inspired by other crowdfunding campaigns. This campaign started as a way for me to share my dad’s product and his story with the world. Kickstarter is the bigger, more popular, more profitable platform.īut the reason I’m switching to Kickstarter vs Indiegogo so late in the game is admittedly also an emotional decision. Even the ad agencies who were open to promoting an Indiegogo campaign admitted this was the case. Backers are more likely to click on Kickstarter ads. Many like Jellop flat-out refused to help promote our Indiegogo campaign – but were more than happy to consider it on Kickstarter. What’s more, advertising agencies are much happier to work on a Kickstarter campaign than the same project featured on Indiegogo. Since more people use Kickstarter and are familiar with it, the chances are better that blogs and media outlets will feature your campaign than an Indiegogo project, too. That’s almost 30 million unique visitors every month. There’s no getting around the fact that Kickstarter kicks ass where it counts the most: visitors, backers, and total funds raised.Īccording to the crowdfunding formula blog, Kickstarter has more than double the monthly web visits than Indiegogo. Maybe that underdog status is what’s pushed Indiegogo to innovate with so many of those features above?īut the bottom line is that Kickstarter is still the king of the crowdfunding game. It’s the Pepsi of crowdfunding while Kickstarter is Coca Cola. Most of us already know that Indiegogo is the smaller platform. With all those great features, why switch platforms? How does Kickstarter compare vs Indiegogo?
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About 790 patients were included in the two chemotherapy-containing arms presented. The nivolumab plus ipilimumab arm was stopped early for undisclosed reasons. 9 Patients were randomly assigned to receive nivolumab plus chemotherapy (either FOLFOX or CAPOX), chemotherapy alone, or nivolumab plus ipilimumab. View largerĬheckMate-649 was a global, randomized phase III trial that included patients with untreated advanced adenocarcinoma of the esophagus, gastroesophageal junction (GEJ), or stomach, regardless of PD-L1 expression. The Figure below illustrates the evolution of immunotherapy in gastro-esophageal cancer in terms of lines of therapy and regulatory approvals. This year, however, the field has taken a giant step forward with the presentation of three randomized trials-CheckMate-649, ATTRACTION-4, and KEYNOTE-590-during the European Society for Medical Oncology Virtual Congress 2020 on September 21. 6,7 The KEYNOTE-062 trial failed to demonstrate superior overall survival (OS) with pembrolizumab compared with chemotherapy, and failed to show an additional benefit of pembrolizumab combined with chemotherapy compared with chemotherapy alone in first-line metastatic gastric cancer. 4,5 Nivolumab and pembrolizumab subsequently received FDA approval in the second-line setting (ATTRACTION-3 and KEYNOTE-181 trials, respectively), but only for esophageal squamous cell carcinoma (ESCC) and-for pembrolizumab-only for patients with tumor PD-L1 combined positive score (CPS) ≥ 10%. 3 The JAVELIN Gastric 100 and JAVELIN Gastric 300 studies compared avelumab to chemotherapy as first-line maintenance and second-line therapy, respectively, and also failed to demonstrate clinical benefit. The KEYNOTE-061 trial showed that pembrolizumab was not superior to chemotherapy in the second-line setting. 1,2 However, subsequent trial results were discouraging. Food and Drug Administration (FDA) approval and nivolumab was approved in Japan in the third-line metastatic setting (KEYNOTE-059 and ATTRACTION-2 trials, respectively), it appeared that immunotherapy would race forward into the first-line and adjuvant therapy settings. Three years ago, when pembrolizumab received U.S. Ongoing research could identify more predictive biomarkers for immunotherapy.Įmerging data from large randomized trials presented recently could lead to major clinical advances with immunotherapy in both the curative and noncurative settings for patients with gastric and esophageal cancers.Adjuvant nivolumab significantly improves median disease-free survival in patients with stage II/III esophageal/gastroesophageal junction cancer treated with trimodality therapy. The combination of immunotherapy and chemotherapy improves overall survival and progression-free survival compared with chemotherapy alone for patients with untreated metastatic gastroesophageal adenocarcinoma and esophageal squamous cell carcinoma.Khorana has had travel, accommodations, or other expenses paid or reimbursed by Janssen, Bayer, Bristol-Myers Squibb, and Seattle Genetics, currently or during the past 2 years.ĭr. Khorana’s institution has conducted any research project funded, in whole or in part, by Merck, Array BioPharma, Bristol-Myers Squibb, and Leap Oncology, currently or during the past 2 years. Khorana has been paid for any consulting or advisory role by Janssen, Halozyme, Bayer, Pfizer, Pharmacyte Biotech, Pharmacyclics, and Seattle Genetics, currently or during the past 2 years. Khorana has been paid honoraria directly by Janssen, Halozyme, Pfizer, Bayer, Nektar, and Medscape, currently or during the past 2 years. Kamath has had travel, accommodations, or other expenses paid or reimbursed by AstraZeneca, Bristol-Myers Squibb, Merck, Foundation Medicine, Guardant Health, Ipsen, and Janssen, currently or during the past 2 years.ĭr. Kamath has been paid for any consulting or advisory role by OncLive and Exelixis, currently or within the past 2 years. You have to get out of the facility and finally escape GLaDOS and Aperture Laboratories. Chell and Wheatley pass through a few test chambers before accidentally reawakening GLaDOS, who has many more tests for you. Chell has been kept in stasis for a long time since the first game ended and is awoken when a tiny personality core named Wheatley tries to break them out of the facility. The puzzles are bigger, the stakes are bigger, the Enrichment Center is bigger. Portal 2 however expands everything from the first game and makes it eleven times better. Portal was an already excellent puzzle game. I don't care.Ĭave Johnson: All right, test's over. But you make her! Hell, put her in my computer. And I will say this, and I'm gonna say it on tape so everybody will hear it a hundred times a day: If I die before you people can pour me in to a computer, I want Caroline to run this place.Ĭave Johnson: Now she'll argue. Brain mapping, artificial inteligence - we should've been working on it thirty years ago. He says what we're all thinking.Ĭave Johnson: The point is, if we can store music on a compact disc, why can't we store a man's inteligence and personality on one? So I have the engineers figuring that one out right now. Cave Johnson: All right, I've been thinking, when life gives you lemons, don't make lemonade!Ĭave Johnson: Make life take the lemons back!Ĭave Johnson: I don't want your damn lemons! What am I supposed to do with these?Ĭave Johnson: Demand to see life's manager! Make life rue the day it thought it could give Cave Johnson lemons! Do you know who I am? I'm the man whose gonna burn your house down - with the lemons!Ĭave Johnson: I'm gonna get my engineers to invent a combustible lemon that'll burn your house down! Doing this lets the battery slowly lose its charge while being stored, which helps to protect the lifespan of the battery. To maintain your rechargeable batteries, it’s best to store them around 40% charge – not fully charged. Just like you separate old and new batteries, you should also separate your rechargeable batteries. If you are not sure about this, you can always use a battery tester to make the job easy. Secondly, you won’t know which batteries have full charge and which ones don’t when you’re looking for a new battery.Īlways separate your old and new batteries to protect the batteries and make it easy to know which are charged. Firstly, the batteries could leak or get damaged. Storing old and new batteries alongside each other can result in two problems. When doing this, make sure that you keep all positive and negative ends (the cathodes and anodes) at the same sides. A good solution is to bundle up batteries together with rubber bands. This could damage batteries and reduce their lifespan. Having a hunch of loose batteries rolling around in a box together is not a good idea. If you do not have these, just use a regular plastic storage container, and try to separate the different batteries from each other. You could also use a battery storage box. The best option is to just use the batteries original containers, placed inside a plastic storage container. Properly contained batteries will prevent any electrical hazards, while maintaining the life of the battery. Never store your batteries in boxes with other items – especially not metal items. Like storing books, batteries need to be carefully contained when they are in storage. Store your batteries in the right containers Maintaining a constant temperature is important for the life of your battery. You also don’t want the batteries to be kept in fluctuating heat conditions. The cold temperature will actually reduce the life of the battery, and the condensation could cause damage. This allows you to maintain a constant room temperature of around 15☌, which is ideal for batteries.Ĭontrary to popular belief, storing batteries in the fridge is not a good idea. Having a climate controlled storage unit is the best option. If you’re storing batteries long-term, then it’s important to pay attention to the temperature of your storage unit. Store batteries at the correct temperature Batteries kept inside equipment can also run flat much quicker. There’s always the chance of battery leakage or corrosion, and you definitely don’t want this to happen inside your electronics. Doing this will help your batteries to last longer, and it will protect your devices. Never put equipment into storage with batteries still in them. The first thing to do when you store batteries is to remove them from whatever they’re powering. Note that the presence of one of these doesn't necessarily make the game itself bad many programs have been quite entertaining despite horrible bugs. The sheer number of possible outcomes makes this type of game-breaking impossible to fully prevent and even the few games lauded for their stability have an occasional hiccup for which the developers can only suggest reloading a saved game. The growing prevalence of Wreaking Havok (especially in the context of facilitating emergent gameplay) can often cause essential game entities to be launched or pushed into places outside the player's reach or destroyed through unexpected methods. The flaw with this approach is that it alienates a sizable chunk of gamers (in this case, gamers who live in a house without a high-speed internet connection). With the advent of integrated network play, developers also seem to favor releasing patch after patch (if they even bother) and treat their paying customers as unpaid testers. In these days of mainstream, multi-million dollar titles, developers seem to favor release dates over thorough quality assurance. if not for game-breaking bugs that slipped past the beta testings ( if there were any) and made them literally unplayable or Nintendo Hard. It was also The Problem with Licensed Games incarnate, since several licensed games actually may not have been as bad as many people say they were. Many games that were made after The '90s seem so much easier because of the reduction in such bugs on average. Game-Breaking Bugs were more prevalent in the earlier days of gaming. The dark side of Good Bad Bugs ( though not necessarily mutually exclusive) and a Griefer's favorite variety, Game-Breaking Bugs are severe bugs that cripple your ability to play the game involved. (this is why I don’t comment things here. for your stay Learn Korean words about the weather with this Korean vocabulary. Here are some examples: List of Vocabulary in Korean Below is a list of the vocabulary and expressions in Korean placed in a table. A vocabulary usually grows and evolves with age, and serves as a useful and fundamental tool for communication and acquiring knowledge. No promises to my boss either for that matter.Īnyway, I’m also making a couple pics here and there kind of Black Lives Matter-y and you can’t stop me, but it does mean that I don’t necessarily use the most recognizible words for the Hanja? (Like for 수 the most obvious one is obviously “math - 수학”) You’re just gonna have to live with that.Īlso I really appreciate likes and reblogs? It’s pretty motivating, but I’m not your boss either so just do your thing. 2 days ago The U Climate in South Korea in august Climate in Seoul in. Korean vocabulary is the set of words you should be familiar with. Feel free to tell me if there’s a style you prefer (and why it’s better for your learning?), but you’re not my boss so no promises. I’m clearly trying out different ways of visualizing things so I hope you don’t mind the inconsistencies. I usually don’t comment on these because they feel big enough already, but whatever. Regarding Customs Charges, policies vary from country to country so please make sure to consult your country’s customs services before placing an order.多樣 - 다양 - Variety / Diversity 數 - 수 - 셀 수 To help you learn these words, each of the Korean words below is written in Hangul (Korean characters) with English romanization and includes the English meaning. Below you’ll find 50 common and basic Korean words for beginners. In the above mentioned cases we cannot offer a refund for your order. Not only will this help you practice reading Korean words, but it will also help you to start speaking in Korean. There are some cases in which we cannot assume responsibility for the failure of delivery, such as: putting down the wrong address, failing to respond to DHL or Custom Services’ inquiries, the parcel being stolen after it had already reached its intended destination, cancelling the order after we’ve already shipped the items. Please contact us at within 3 days of receiving the parcel, in case you encounter any troubles with your order. In case we are at fault for any issues with your order, we take full responsibility for your items and we offer a full refund or exchange/re-send the items. Your items are packed with the utmost care and you will be provided with a tracking number once the item is on its way to you Orders are shipped via DHL Express which normally takes 2-5 business days. That way you can revise the vocabulary terms and see them used in sentences.Īt the end of the challenge, you will have enriched your Korean vocabulary by over 1400 key-words and phrases that you can mix and match in your daily conversations. Each lesson covers dialogues, pronunciation, vocabulary, grammar. Memorizing new words is essential but you also need to put this knowledge to use! For that very purpose, we have included Crossword Puzzles and Word Quizzes for every 10 Units. This is an elementary-level Korean language course, consisting of 5 lessons with 4. Practice your Hangeul writing skills by repeatedly writing down the terms. Anything goes, as long you keep working on it! The Word Sheets’ difficulty level increases slightly as you progress to the final sections. You can choose to complete 1 Word Sheet per day or if life gets too busy, perhaps you can try memorizing 2 words a day and finish 1 Word Sheet per week. Carro’s 100 Days Korean Vocab Challenge is a supplementary material to Korean For All textbook, a chance to take your Korean learning one step further.Įxpand your Korean vocabulary with 100 Topic based Word Sheets. We are here to provide you with the support, space, accountability, structure & relationships that are so important for accomplishing your. No matter your starting point, challenges, abilities, goals. Human connection is at the center of what we do & how we help you find balanced self care. Befit Physiotherapy is run by experienced physiotherapists offering the highest quality care to meet the needs of children, adults, seniors, sports, spinal and general patients.We start with a detailed assessment aimed at the cause of the ailment or injury and then a plan is created to treat the pain and also to prevent the re-occurrence of the problem.We always keep it authentic, personal & judgement free. Maintaining it's "OG" status, this facility is where BeFit began to spread it's wings and evolve into the brand it is today. Maintaining it's "OG" status, this facility is where BeFit began to spread it's wings and evolve into the brand it is today.ABOUT BEFIT DOUBLE BAY Double Bay has been the evolution of what started out as the the original BeFit Training studio, in the suburbs of Bellevue Hill many years ago. Kíktu til okkar í Mörkina 1 Reykjavík eða Dalsbraut 1 Akureyri almanya satilik ev sitesiABOUT BEFIT DOUBLE BAY Double Bay has been the evolution of what started out as the the original BeFit Training studio, in the suburbs of Bellevue Hill many years ago. Kíktu til okkar í Mörkina 1 Reykjavík eða Dalsbraut 1 AkureyriVisit the post for more. Prior to proposing BEFIT, the European Commission will table the other proposals mentioned above.Visit the post for more. Given the European Commission's communication in the area of business taxation, it is likely that the proposal will be put forward in 2023. The BEFIT proposal is yet to be published by the European Commission. Scrubs and cleans concrete and removes oil.Scrubs and cleans ceramic tile and grout.Dry cleans carpet and removes allergens.Floor Machines Type: Scrubber Polisher Handle Type: T-Grip Brush Diameter: 12 Power Capacity: 0.5 hp. The Oreck Orbiter makes it simple to sand, refinish, strip, scrub, wax, and polish all floor surfaces, as well as deep clean your carpets. Suitable for use with various accessories including brushes, pads, bonnets, shampoos, and cleaning solutions (sold separately) Revitalizes vinyl, brick, slate, and stone floors.Product dimensions: 49.6 x 13.6 x 9.7 inches Weighs 24 pounds has 13" cleaning path and 3/4-horsepower, 5.4-amp motor.50-foot power cord enables the floor machine to cover larger area without changing outlets than machines with shorter cords. The Oreck Orbiter 12 inch electric floor buffer is one of our best-selling machines because its great for light duty commercial use as well as. The patented Oreck ORBITER utilizes a unique - vibrating, buffing -action to deliver outstanding performance in a compact 12 inch machine head producing.Orbital drive oscillates the brush or pad (sold separately) at up to 175 RPM to buff, clean, polish, sand, scrub, strip, or wax floors without twisting, marking, or gouging.Floor buffer used for cleaning wood, vinyl, tile, and other hard floors and for dry-cleaning and loosening dirt from carpeted floors.Use it to sand, refinish, strip, scrub, wax, and polish all floor surfaces. Oreck Orbiter Ultra Multi-Purpose Floor Machine makes your ceramic tile, marble, terrazzo and hardwood floors look new. In 1970, Lithium was approved by the United States Food and Drug Administration (FDA) for the treatment of bipolar disorder, which remains its primary use in the United States. Ī bottle of lithium medicine containing 300 mg capsules of lithium carbonate. In 2019, it was the 205th most commonly prescribed medication in the United States, with more than 2 million prescriptions. It is on the World Health Organization's List of Essential Medicines, and is available as a generic medication. Use of lithium for mental disorders was re-established (on a different theoretical basis) in 1948 by John Cade in Australia. Its use in the treatment of mental disorders began with Carl Lange in Denmark and William Alexander Hammond in New York City, who used lithium to treat mania from the 1870s onwards, based on now-discredited theories involving its effect on uric acid. In the nineteenth century, lithium was used in people who had gout, epilepsy, and cancer. How lithium works is not specifically known. Lithium salts are classified as mood stabilizers. The United States Food and Drug Administration categorizes lithium as having positive evidence of risk for pregnancy and possible hazardous risk for lactation. The American Academy of Pediatrics lists lithium as contraindicated for pregnancy and lactation. The use of lithium while breastfeeding is controversial however, many international health authorities advise against it, and the long-term outcomes of perinatal lithium exposure have not been studied. Lithium is teratogenic, especially during the first trimester of pregnancy and at higher dosages. If levels become too high, diarrhea, vomiting, poor coordination, sleepiness, and ringing in the ears may occur. Blood level monitoring is recommended to decrease the risk of potential toxicity. Serious side effects include hypothyroidism, diabetes insipidus, and lithium toxicity. Ĭommon side effects include increased urination, shakiness of the hands, and increased thirst. In these disorders, it sometimes reduces the risk of suicide. Certain lithium compounds, also known as lithium salts, are used as psychiatric medication, primarily for bipolar disorder and for major depressive disorder. Alternatively, to navigate to it in Finder, hold down Option, click the Go menu, and select Library (which is hidden by default), and then follow the rest of the path. (~/Library refers to the Library folder within your home directory.) You can open it from the Finder by pressing Cmd-Shift-G and copying in the path. The default location of the Startup folder is ~/Library/Group Containers/UBF8T346G9.Office/User Content/Startup/Word. If that's the case, you should reset the path to the default location. Note that the path should not include “Zotero” in any way, and if it does you previously configured it incorrectly. You can then open a new File Explorer dialog and paste the path into the address bar to open the Startup folder. Click Cancel to close the dialog without making changes. In the window that opens, click the whitespace to the right of the path in the location bar at the top and copy the complete path to the clipboard by pressing Ctrl-C. The Startup folder should be listed there. In the Word ribbon, click the File tab, click Options, and click Advanced. If changes you make to the Startup folder aren't taking effect, you can confirm that Word isn't set to a different location. From there you can navigate to Microsoft\Word\Startup. The AppData folder may be hidden on your system, but you can get there by opening the Windows File Explorer, typing %AppData% in the address bar, and pressing Enter, which will take you into the Roaming directory. The default location of the Startup folder is C:\Users\::username::\AppData\Roaming\Microsoft\Word\Startup, where ::username:: is your computer username. |